Overview:

Presently there is no cure for Multiple Sclerosis but many Disease Modifying Therapies do exist.  Below please find the table of the Disease Modifying Therapies approved for usage by the US Food And Drug Administration (FDA).  Therapies are available in oral (pill form), Hypodermic Injection and Intravenous Infusion treatment formats.

Disease Modifying Therapies or DMT’s work to alter the course of the disease.  The medications work in differing ways, all have side effects and risks associated with usage.

The general concept of the DMT’s is to prevent exacerbation’s (MS Attacks) and thus prevent damage to the Central Nervous System and progression of the disease.

Side Effects and Risks:

All of the FDA approved treatments for Multiple Sclerosis have side effects and risks as do any medications.  The side effects and risks vary with each therapy and it is recommended to research the therapies and discuss the options available to you with your health care provider.

Many of the side effects of these therapies can be managed in a variety of ways which may also be discussed with your health care team.

DMT ImageEfficacy of the FDA Approved Therapies:

The efficacy (effectiveness) of the FDA approved therapies vary and all have passed clinical trial testing.  While there is no DMT therapy that is 100% effective, efficacy of the therapies does vary and can be dependent on a variety of factors.  When looking towards DMT therapies other life modifications such as dietary, exercise and other alterations can be helpful in coping with Multiple Sclerosis and attempting to maintain general good health and wellness.  All options should be discussed with your health care team to develop a protocol for you as an individual.

Your health care provider will also explain to you the monitoring options that help let you and the health care team know if a therapy you are engaged in is having the desired impacts on slowing progression of the disease.

Early Intervention Matters:

 

Selecting A Disease Modifying Therapy:

Availability and Cost:

Availability of disease modifying therapies may vary in your country. Check with your care provider for details.

Depending on your health care insurance it is wise to engage your health care team at the necessary levels to evaluate the progression of your Multiple Sclerosis and help select a DMT that is suitable and has the best thought of efficacy given your current health conditions.  Your health care team can also be your advocate to your insurance carrier.

There are also many options available in respect to obtaining therapies should the insurance carrier have issues in as far as coverage provided.  These include financial assistance from a variety of sources as well as from many of the manufacturers of the medications.  Your health care provider can assist you in engaging in a therapy and assist you in navigating the options that exist for you given your current location and financial circumstances.

Advisable Communications & Resources:

It is advisable to make sure your health care team is cohesive as MS can be a very complex affliction.  The variety of symptoms and results of “MS Attacks” varies from individual to individual.  The MS Unites website has a variety of natural ways explained to help cope with the disease.  However, it is often advisable to have a cohesive health care team as they are your front-line in managing MS. Your personal Physician, a Neurologist,  Ophthalmologist, Dietician, Physical Therapist & Mental Health Care professional are wise to have in place.

 List of FDA Approved Therapies:

Therapy
Name
Generic
Name
Dose
Frequency
Dosage Delivery Product Website
Year
Approved
Manufacturer
Name
Aubagio Teriflunomide Once Daily 7mg
or
14mg
Oral Pill www.aubagio.com 2012 Genzyme
A Sanofi company
Avonex Interferon
Beta-1a
Once Weekly 30mcg Injection
(intramuscular)
www.avonex.com 1996 Biogen
Betaseron Interferon
Beta-1b
Every Other
Day
250mcg Injection
(subcutaneous)
www.betaseron.com 1993 Bayer Health Care
Pharmaceuticals Inc.
Copaxone Glatiramer
Acetate
Once Daily
or
Three Times Weekly
20,000
mcg
or
40,000
mcg
Injection
(subcutaneous)
www.copaxone.com 1996 Teva Neuroscience
Extavia Interferon
Beta-1b
Every Other
Day
250mcg Injection
(subcutaneous)
www.extavia.com 2009 Novartis
Pharmaceuticals Corp.
Gilenya Fingolimod Every Other
Day
0.5 mg Oral Capsule www.gilenya.com 2010 Novartis
Pharmaceuticals Corp
Glatopa Glatiramer
Acetate
Once Daily 20,000
mcg
Injection
(subcutaneous)
www.glatopa.com 2010 Sandoz/Novartis
Pharmaceuticals Corp
Lemtrada Alemtuzumab 5 Days In A Row
1 Year Later:
3 Days In A Row
12mg Intravenous Infusion www.lemtrada.com 2014 Genzyme
A Sanofi company
Plegridy Pegylated Interferon
Beta-1a
Every 14 Days
(2 weeks)
125mcg Injection
(subcutaneous)
www.plegridy.com 2014 Biogen
Rebif Interferon
Beta-1a
Three Times Weekly 44mcg Injection
(subcutaneous)
www.rebif.com 2002 EMD Serono Inc. and
Pfizer Inc.
Tecfidera Dimethyl
Fumarate
Twice Daily
120mg First Week
240mg Thereafter
120mg
240mg
Oral Capsule www.tecfidera.com 2013 Biogen
Tysabri Natalizumab Every 4 weeks 300mg Intravenous Infusion www.tysabri.com 2006 Biogen

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